Clinical Trials

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Clinical Trials can be another treatment source as veterinarians discover new ways to diagnose cancer faster and improve the treatment outcomes. These veterinary clinical trials could be promising new treatments, drugs or procedures. Often the treatment costs in a clinical trial are covered by the clinical trial sponsor. Review this page below for potential clinical trials in your area as they relate to TCC. The clinical trial link will provide you more detailed information on the specific trial. Please reach out to the contact to obtain additional information.

Study Name

Information

New Clinical Trial for Dogs with Bladder Cancer to determine the antitumor effects of a CDK9 inhibitor named enitociclib. This is the first study of its kind as this type of medication (CDK9 inhibitor) is a brand new approach to treating TCC.

Location: Purdue University, Lafayette, Indiana

Recruitment is open

Primary Investigator:
Dr. Debbie Knapp

Primary Study Contact:
Pet owners and veterinarians that are interested in the trial, who would like more information, or have questions are asked to contact our Clinical Trial nurses, Lindsey Fourez or Araynna Holland at 765-494-1130 or email Ms. Fourez at lfourez@purdue.edu. Call the Purdue University Veterinary Hospital at 765-494-1107 to schedule an appointment.

EGFR/HER2 Vaccine (Yale Vaccine) developed by Dr. Mark Mamula at Yale for dogs has potential to inhibit EGFR signalling, boost antibodies and inhibit tumor growth. Consists of two shots, 3 weeks apart. Can be given along with chemotherapy or radiation treatments. Minimal side effects. Published study

EGFR protein is overexpressed in canine Transitional Cell Carcinoma. Preliminary data studying Osteosarcoma and Hemangiosarcoma is encouraging.

Immunotherapy for Urothelial Carcinoma in Dogs - (all costs are covered by the trial) - to evaluate the tolerability and efficacy of a novel anti-PD1 immunotherapy in dogs with urothelial carcinoma.

Phase I Clinical Trial of NCGC00413972 (NIH 972) in Dogs with Spontaneously Occurring Sarcomas

Location: Flint Animal Cancer Center, Colorado State University, Fort Collins, CO

Primary Study Contact: CSU Oncology Clinical Trials csuoncologytrials@colostate.edu 1-970-297-4001

Safety of B7H3 CAR T cells in Dogs with Spontaneous Cancer

Location: University of Illinois, College of Veterinary Medicine, Urbana, IL

Primary Study Contact: Clinical Trials Coordinator, Rebecca Kamerer, Email: rmoss81@illinois.edu Phone:(217) 300-6453

THERAPEUTIC TRIAL FOR DOGS WITH BLADDER CANCER - Nutritional Supplement added to current treatment


Dogs with Bladder Cancer - evaluating a probiotic to improve cancer care and/or outcomes;

 

Probiome for Canine Bladder Cancer; This study is heavily subsidized allowing your dog to be treated with Vinblastine for very little cost to the pet owner.

Location: North Carolina State University, Raleigh, NC

Principal Investigator: Claire Wiley: UCClinicalTrials@ncsu.edu

Location: North Carolina State University, Raleigh, NC
Primary Study Contact: Ashley Fuhrer, Phone: 919-515-3634, email: cvmclinicalstudies@ncsu.edu

Location: North Carolina State University, Raleigh, NC
Primary Study Contact: Ashley Fuhrer, Phone: 919-515-3634, email: cvmclinicalstudies@ncsu.edu

Location #2: University of Missouri, Veterinary Health Center, Colombia, MO
Primary Study Contact Email: cvmclinicaltrials@missouri.edu

Location #3: Ohio State University, Veterinary Medical Center, Columbus, OH
Primary Study Contact Email: CVM-ClinicalTrials@osu.edu

Watch this short video describing the trial

Experimental immunotherapy (IL-12) for the treatment of bladder cancer in dogs

Location: North Carolina State University, Raleigh, NC

Principal Investigator: Dr. Paul Hess, cvmclinicalstudies@ncsu.edu or 919-515-3634

Cancer Immunotherapy: Phase 1 trial for a new canine immunotherapy drug

Location: University of Minnesota, College of Veterinary Medicine, St. Paul, MN

Recruitment open

Primary Study Contact:
Amber Winter, CVT
Email: alwinter@umn.edu
612-624-1352

 

Radiopharmaceutical Therapy: Combination Radiation and Immunotherapy for Advanced Cancer

Location: University of Wisconsin Veterinary Care, Madison, Wisconsin

Call the Oncology Service for Additional Information: (608) 890-0422 or email ONCCLINICALTRIALS@VETMED.WISC.EDU

Artificial neobladder placement for dogs with resectable lower urinary tract tumors


Pilot study of resiniferatoxin administered into the bladder to manage lower urinary tract discomfort in dogs with bladder transitional cell carcinoma

Location: Animal Medical Center, New York, NY

Primary Study Contact:
Dr. Chick Weisse at 212-838-8816 or email chick.weisse@amcny.org.

Location: Animal Medical Center, New York, NY

Primary Study Contact:
Dr. Nicole Liebman at 212-329-8740 or email nicole.leibman@amcny.org

Clinical and Safety Evaluation of Multiple Intravenous Administrations of Immunocidin® in Cats and Dogs with Malignancies

Location: Veterinary Cancer Care, Santa Fe, New Mexico
info@vetcancercare.com
505-982-4492